Ovarian cancer screening—Current status, future directions
نویسندگان
چکیده
منابع مشابه
Ovarian cancer screening—Current status, future directions☆
Evidence of a mortality benefit continues to elude ovarian cancer (OC) screening. Data from the US Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial which used a screening strategy incorporating CA125 cut-off and transvaginal ultrasound has not shown mortality benefit. The United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) is using the Risk of Ovarian Ca...
متن کاملFuture Directions for Immunotherapy in Ovarian Cancer
Immunotherapies involving cellular and checkpoint inhibitor approaches are under investigation in ovarian cancer and preliminary results suggest evidence of clinical benefit. Assumptions in the past of low immunogenicity of ovarian cancer appear to be changing as our new awareness of immune function activity with ovarian cancer, tumor microenvironment and molecular signaling is becoming evident...
متن کاملFuture directions for the management of ovarian cancer.
Although the results of treatment of ovarian cancer have improved over the past 20 years with the introduction of platinum and more recently taxoid-based chemotherapy, the majority of patients still die of this disease. Further improvements may be expected by the incorporation of other new agents in more imaginative schedules, perhaps including a sequential approach or neoadjuvant regimens. Oth...
متن کاملCurrent and future directions of clinical trials for ovarian cancer.
BACKGROUND The management of ovarian cancer includes a combination of surgery and chemotherapy. The majority of clinical trials have historically addressed questions pertaining to the selection, dosing, and schedule of chemotherapy agents. METHODS In this report, a comprehensive review of the major clinical trials in ovarian cancer is performed. The increasing data and clinical experience in ...
متن کاملOvarian cancer: state of the art and future directions.
The median survival of patients with ovarian cancer has increased steadily, mainly due to a multidisciplinary approach including surgery and chemotherapy. This editorial article summarizes the important messages taken from clinical research performed in this field over the last 15 years. It deals with the following issues: screening, prevention, management of early and advanced disease, mainten...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gynecologic Oncology
سال: 2014
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2013.11.030